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Green Bottle Fly

Lucilia sericata

FDA-approved for medical maggot therapy. Eats dead tissue, kills MRSA, stimulates healing.

Curated and rated by Sheriff Six-Legs and The Wild Pest field team · Six Legs Score™ (84/100, Outlaw tier) · Published Apr 25, 2026 · Updated Apr 28, 2026 · Released CC BY 4.0

84Six Legs
Six Legs Score™
84 / 100

The green bottle fly is the FDA-approved species used in modern medical maggot debridement therapy — sterile lab-reared larvae are placed in chronic non-healing wounds where they consume dead tissue, secrete antimicrobial compounds that kill MRSA and other bacteria, and stimulate granulation and healing. The therapy was used informally for centuries (Civil War surgeons noticed wounds with maggot colonization healed better) and was reintroduced into modern medicine in the 1990s. The species is also one of the most-used tools in forensic entomology — adult flies are typically the first insects to colonize human remains and the larval development timeline is used to estimate post-mortem interval.

A green bottle fly (Lucilia sericata), brilliant metallic green-bronze body with red-orange compound eyes and translucent wings, six legs, side profile.
Green Bottle FlyWikimedia Commons · CC BY-SA 4.0
Size
Adult 8-12 mm
Lifespan
Adult 2-4 weeks
Range
Cosmopolitan in temperate Northern Hemisphere
Diet
Adults: nectar, animal exudates. Larvae: decomposing animal tissue (also living tissue in sheep blow fly strike).
Found in
Near carrion, garbage, decaying animal matter; in sheep flocks; in clinical maggot therapy programs

Field guide

Lucilia sericata — the green bottle fly, also called the sheep blow fly — is one of the most consequential medical insects in modern healthcare and a centerpiece species of forensic entomology. Adults are 8-12 mm with brilliant metallic green-bronze bodies and red-orange compound eyes; the species is one of the most familiar 'green bottle' flies in temperate human environments. The species has two major roles in modern human industry. First, MEDICAL MAGGOT THERAPY: green bottle fly larvae are FDA-approved (since 2004) for clinical wound debridement therapy. Sterile lab-reared larvae are placed in chronic non-healing wounds (diabetic foot ulcers, pressure sores, post-surgical wounds, burn wounds) where they perform three therapeutic functions simultaneously: (1) DEBRIDEMENT — they consume dead, necrotic, and infected tissue while leaving healthy tissue alone (the larvae have specific enzymatic preferences for dead protein); (2) ANTIBACTERIAL — they secrete potent antimicrobial peptides (notably defensin-like compounds) that kill MRSA, Pseudomonas, Streptococcus, and other resistant bacteria that conventional antibiotics struggle with; (3) STIMULATION — they secrete growth factors that accelerate granulation tissue formation and wound contraction. The technique is used clinically across thousands of US, UK, and European hospitals and is one of the most-cited examples of 'living drug' medical biotechnology. Second, FORENSIC ENTOMOLOGY: green bottle flies are typically the FIRST insects to colonize a fresh human corpse — adults arrive within minutes of death (drawn by sulfur volatiles from beginning decomposition) and lay eggs on the body. The precise developmental timeline of green bottle fly larvae (egg → 1st instar → 2nd → 3rd → pupa → adult) is temperature-dependent and well-characterized, allowing forensic entomologists to estimate post-mortem interval (time of death) to within hours for bodies in the first 1-2 weeks. The species is a foundational organism in modern forensic entomology curricula. The species also has historical significance in agriculture — sheep blow fly strike (where larvae develop in living sheep wool and damage the host) is a major Old World sheep industry concern.

5 wild facts on file

Green bottle fly larvae are FDA-approved (since 2004) for clinical wound debridement therapy — used in thousands of US, UK, and European hospitals.

AgencyUS FDA2004Share →

Larvae secrete antimicrobial peptides that kill MRSA, Pseudomonas, Streptococcus, and other antibiotic-resistant bacteria — solving infections conventional antibiotics struggle with.

AgencyAmerican Medical AssociationShare →

Civil War surgeons noticed wounds with maggot colonization healed better — modern medicine forgot the technique for a century, then reintroduced it in the 1990s.

AgencyAmerican Medical AssociationShare →

Green bottle flies are typically the FIRST insects to colonize a fresh human corpse — arrive within minutes of death and the larval developmental timeline is the foundational forensic-entomology PMI tool.

AgencyAmerican Board of Forensic EntomologyShare →

Larvae have specific enzymatic preferences for DEAD protein — they consume necrotic tissue while leaving healthy tissue alone, making them precise wound-cleaning tools.

AgencyRoyal Society of ChemistryShare →
Cultural file

The green bottle fly is one of the most clinically and forensically significant insect species in modern science. The 2004 FDA approval of maggot therapy is a flagship case in 'living drug' regulation, and the species is the centerpiece organism in modern forensic entomology training programs at the American Board of Forensic Entomology and similar institutions worldwide.

Sources

AgencyUS FDAAgencyAmerican Board of Forensic Entomology
Six’s Field Notes

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